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Obatoclax Rescues FUS-ALS Phenotypes in iPSC-Derived Neurons by Inducing Autophagy

Aging is associated with the disruption of protein homeostasis and causally contributes to multiple diseases, including amyotrophic lateral sclerosis (ALS). One strategy for restoring protein homeostasis and protecting neurons against age-dependent diseases such as ALS is to de-repress autophagy. BE...

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Bibliografische gegevens
Hoofdauteurs: Cristina Marisol Castillo Bautista, Kristin Eismann, Marc Gentzel, Silvia Pelucchi, Jerome Mertens, Hannah E. Walters, Maximina H. Yun, Jared Sterneckert
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2023-09-01
Reeks:Cells
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Online toegang:https://www.mdpi.com/2073-4409/12/18/2247
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