A Systematic Review of Transcriptional Dysregulation in Huntington’s Disease Studied by RNA Sequencing
Huntington’s disease (HD) is a chronic neurodegenerative disorder caused by an expansion of polyglutamine repeats in exon 1 of the Huntingtin gene. Transcriptional dysregulation accompanied by epigenetic alterations is an early and central disease mechanism in HD yet, the exact mechanisms and regula...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2021-10-01
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| Serie: | Frontiers in Genetics |
| Soggetti: | |
| Accesso online: | https://www.frontiersin.org/articles/10.3389/fgene.2021.751033/full |
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