Design of a multi-epitope vaccine against drug-resistant mycobacterium tuberculosis and mycobacterium bovis using reverse vaccinology

Abstract The global burden of Mycobacterium tuberculosis (M. tuberculosis) and Mycobacterium bovis (M. bovis), the rise of drug-resistant strains, necessitates an urgent need for developing more effective vaccines. This study employed an in-silico approach to design a multi-epitope vaccine targeting...

Полное описание

Библиографические подробности

Главные авторы:	Eva Akurut, Yahaya Gavamukulya, Julius Mulindwa, Moses Isiagi, Ronald Galiwango, Mudarshiru Bbuye, Ibra Lujumba, Davis Kiberu, Patricia Nabisubi, Grace Kebirungi, Andrew Kambugu, Barbara Castelnuovo, Gyaviira Nkurunungi, Daudi Jjingo, Brenda Oketch, David Patrick Kateete, Gerald Mboowa
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Portfolio 2025-07-01
Серии:	Scientific Reports
Предметы:	Mycobacterium tuberculosis Mycobacterium bovis Vaccines BCG Reverse vaccinology Molecular Docking
Online-ссылка:	https://doi.org/10.1038/s41598-025-11768-3
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