Viable cell density as an indicator for dynamic feeding strategy in fed-batch and perfusion CHO cell culture
Abstract The general approach to industrial production of monoclonal antibodies is fed-batch culture using Chinese Hamster Ovary (CHO) cells. Perfusion culture is also attracting attention as a next-generation culture method. In these culture methods, optimization of amino acid and glucose concentra...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
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Nature Portfolio
2025-12-01
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| Serie: | Scientific Reports |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1038/s41598-025-28316-8 |
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