Comparison of 3D and 4D robustly optimized proton treatment plans for non-small cell lung cancer patients with tumour motion amplitudes larger than 5 mm

Background and purpose: There is no consensus about an ideal robust optimization (RO) strategy for proton therapy of targets with large intrafractional motion. We investigated the plan robustness of 3D and different 4D RO strategies. Materials and methods: For eight non-small cell lung cancer patien...

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Principais autores:	Saskia Spautz, Leon Haase, Maria Tschiche, Sebastian Makocki, Christian Richter, Esther G.C. Troost, Kristin Stützer
格式:	Artigo
语言:	Inglês
出版:	Elsevier 2023-07-01
丛编:	Physics and Imaging in Radiation Oncology
主题:	Proton therapy Robust optimization Lung cancer Large intrafraction motion Interfraction changes
在线阅读:	http://www.sciencedirect.com/science/article/pii/S2405631623000568
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