Comparison of 3D and 4D robustly optimized proton treatment plans for non-small cell lung cancer patients with tumour motion amplitudes larger than 5 mm

Background and purpose: There is no consensus about an ideal robust optimization (RO) strategy for proton therapy of targets with large intrafractional motion. We investigated the plan robustness of 3D and different 4D RO strategies. Materials and methods: For eight non-small cell lung cancer patien...

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Hlavní autoři:	Saskia Spautz, Leon Haase, Maria Tschiche, Sebastian Makocki, Christian Richter, Esther G.C. Troost, Kristin Stützer
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2023-07-01
Edice:	Physics and Imaging in Radiation Oncology
Témata:	Proton therapy Robust optimization Lung cancer Large intrafraction motion Interfraction changes
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2405631623000568
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