Sec17/Sec18 act twice, enhancing membrane fusion and then disassembling cis-SNARE complexes
At physiological protein levels, the slow HOPS- and SNARE-dependent fusion which occurs upon complete SNARE zippering is stimulated by Sec17 and Sec18:ATP without requiring ATP hydrolysis. To stimulate, Sec17 needs its central residues which bind the 0-layer of the SNARE complex and its N-terminal a...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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eLife Sciences Publications Ltd
2017-07-01
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| Schriftenreihe: | eLife |
| Schlagworte: | |
| Online-Zugang: | https://elifesciences.org/articles/26646 |
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