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Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus.

Systemic lupus erythematosus (SLE) is a genetically complex disease with heterogeneous clinical manifestations. A polymorphism in the STAT4 gene has recently been established as a risk factor for SLE, but the relationship with specific SLE subphenotypes has not been studied. We studied 137 SNPs in t...

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Príomhchruthaitheoirí: Kimberly E Taylor, Elaine F Remmers, Annette T Lee, Ward A Ortmann, Robert M Plenge, Chao Tian, Sharon A Chung, Joanne Nititham, Geoffrey Hom, Amy H Kao, F Yesim Demirci, M Ilyas Kamboh, Michelle Petri, Susan Manzi, Daniel L Kastner, Michael F Seldin, Peter K Gregersen, Timothy W Behrens, Lindsey A Criswell
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Public Library of Science (PLoS) 2008-05-01
Sraith:PLoS Genetics
Rochtain ar líne:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000084&type=printable
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