Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus.

Systemic lupus erythematosus (SLE) is a genetically complex disease with heterogeneous clinical manifestations. A polymorphism in the STAT4 gene has recently been established as a risk factor for SLE, but the relationship with specific SLE subphenotypes has not been studied. We studied 137 SNPs in t...

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Autori principali:	Kimberly E Taylor, Elaine F Remmers, Annette T Lee, Ward A Ortmann, Robert M Plenge, Chao Tian, Sharon A Chung, Joanne Nititham, Geoffrey Hom, Amy H Kao, F Yesim Demirci, M Ilyas Kamboh, Michelle Petri, Susan Manzi, Daniel L Kastner, Michael F Seldin, Peter K Gregersen, Timothy W Behrens, Lindsey A Criswell
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Public Library of Science (PLoS) 2008-05-01
Serie:	PLoS Genetics
Accesso online:	https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000084&type=printable
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