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De novo synthesis of hepatitis B virus nucleocapsids is dispensable for the maintenance and transcriptional regulation of cccDNA

Background & Aims: Chronic HBV infection cannot be cured by current therapeutics owing to their limited ability to reduce covalently closed circular (ccc)DNA levels in the livers of infected individuals. Therefore, greater understanding of the molecular determinants of cccDNA formation and persi...

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Detaylı Bibliyografya
Asıl Yazarlar: Thomas Tu, Benno Zehnder, Bingqian Qu, Stephan Urban
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2021-02-01
Seri Bilgileri:JHEP Reports
Konular:
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2589555920301294
Etiketler: Etiketle
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