The effects of inflammation on connexin 43 in chronic Chagas disease cardiomyopathy

BackgroundCardiac arrhythmias are the main cause of sudden death due to Chronic Chagasic Cardiomyopathy (CCC). Here we investigated alterations in connexin 43 (Cx43) expression and phosphorylation in cardiomyocytes as well as associations with cardiac arrhythmias in CCC.MethodsC57Bl/6 mice infected...

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Hlavní autoři:	Breno Cardim Barreto, Maria Vitória Gomes das Neves, Carine Machado Azevedo Cardoso, Cássio Santana Meira, Pâmela Santana Daltro, Cláudio Pereira Figueira, Girlaine Café Santos, Daniela Nascimento Silva, Fábio Távora, João David de Souza Neto, Simone Garcia Macambira, Paul D. Lampe, Keyla Cristiny da Silva Coutinho, Tais Hanae Kasai Brunswick, Ricardo Ribeiro dos Santos, Antônio Carlos Campos de Carvalho, Milena Botelho Pereira Soares
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-07-01
Edice:	Frontiers in Immunology
Témata:	Chagas disease cardiomyopathy connexin 43 arrhythmias inflammation
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1440662/full
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