Network pharmacology, molecular docking, and in vivo experiments reveal the effects of Polygonati Rhizoma on periodontitis

Abstract This study explores Polygonati Rhizoma’s therapeutic potential against periodontitis using network pharmacology, molecular docking, and experimental validation to uncover its mechanisms. Active ingredients and targets of Polygonati Rhizoma were sourced from TCMSP and DrugBank, while periodo...

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Podrobná bibliografie

Hlavní autoři:	Qunli Ren, Xiaolan Li, Jingtong Wang, Qian Wang, Fangzhou Liu, Bin Zeng, Pan Gao, Yingzhe Li, Menglin Song, Zhongjia Tian, Bin Chen, Jianguo Liu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2026-02-01
Edice:	Scientific Reports
Témata:	Polygonati Rhizoma Periodontitis Network pharmacology Molecular docking Gut microbiota Alveolar bone loss
On-line přístup:	https://doi.org/10.1038/s41598-026-40597-1
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