SIRT1 Activation Suppresses Corneal Endothelial–Mesenchymal Transition via the TGF-β/Smad2/3 Pathway

Endothelial–mesenchymal transition (EnMT) is the transversion of endothelial cells to mesenchymal cells under certain physiological or pathological conditions. When EnMT occurs in the corneal endothelium, corneal endothelial cells (CECs) lose their normal function and thus cannot maintain corneal cl...

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Detalhes bibliográficos

Principais autores:	Yi Yu, Ruilin Guo, Jie Ling, Chenjia Xu, Minglu Ma, Xiaojuan Dong, Jing Wu, Ting Huang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2024-12-01
coleção:	Current Issues in Molecular Biology
Assuntos:	SIRT1 endothelial–mesenchymal transition corneal endothelial cells TGF-β/Smad2/3
Acesso em linha:	https://www.mdpi.com/1467-3045/46/12/827
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