Intranasal Immunization with Recombinant Hemagglutinin of Influenza A/H5 Virus Complexed with Novochizol Induces Virus-Neutralizing Antibodies and Protects Animals from Lethal Viral Challenge

<b>Background:</b> Avian influenza is a critical zoonotic infection threatening both the poultry industry and global public health. While traditional intramuscular vaccines elicit systemic immunity, they often fail to provide robust local protection at mucosal surfaces. There is thus significant int...

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主要な著者:	Nadezhda B. Rudometova, Ksenia I. Ivanova, Vladislav V. Fomenko, Andrey P. Rudometov, Lyubov A. Kisakova, Denis N. Kisakov, Elena V. Yakovleva, Vladimir A. Yakovlev, Kristina P. Makarova, Danil I. Vakhitov, Mariya B. Borgoyakova, Ekaterina V. Starostina, Boris N. Zaitsev, Victoria R. Litvinova, Stepan A. Pyankov, Tatiana N. Ilyicheva, Alexander A. Ilyichev, Andrei S. Gudymo, Vasiliy Yu. Marchenko, Nariman F. Salakhutdinov, Aleksandr P. Agafonov, Larisa I. Karpenko
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2026-05-01
シリーズ:	Pharmaceutics
主題:	influenza A/H5 virus hemagglutinin intranasal immunization Novochizol
オンライン･アクセス:	https://www.mdpi.com/1999-4923/18/6/669
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