Efficient Multiplex Gene Repression by CRISPR-dCpf1 in Corynebacterium glutamicum

Corynebacterium glutamicum is an important workhorse for industrial production of diversiform bioproducts. Multiplex control of metabolic pathway genes is crucial for maximizing biosynthesis of desired products. However, few tools for simultaneously regulating multiple genes in C. glutamicum have be...

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Hlavní autoři:	Mingyue Li, Jiuzhou Chen, Yu Wang, Jiao Liu, Jingwen Huang, Ning Chen, Ping Zheng, Jibin Sun
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2020-04-01
Edice:	Frontiers in Bioengineering and Biotechnology
Témata:	Corynebacterium glutamicum CRISPR-dCpf1 multiplex gene repression metabolic engineering lysine
On-line přístup:	https://www.frontiersin.org/article/10.3389/fbioe.2020.00357/full
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