Advances in Allogeneic Cancer Cell Therapy and Future Perspectives on “Off-the-Shelf” T Cell Therapy Using iPSC Technology and Gene Editing

The concept of allogeneic cell therapy was first presented over 60 years ago with hematopoietic stem cell transplantation. However, complications such as graft versus host disease (GVHD) and regimen-related toxicities remained as major obstacles. To maximize the effect of graft versus leukemia, whil...

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Principais autores:	Yoshiki Furukawa, Yasuharu Hamano, Shuichi Shirane, Shintaro Kinoshita, Yoko Azusawa, Jun Ando, Hiromitsu Nakauchi, Miki Ando
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-01-01
coleção:	Cells
Assuntos:	allogeneic cell cancer immunotherapy CART therapy donor lymphocyte infusion gene editing graft versus host disease graft versus leukemia
Acesso em linha:	https://www.mdpi.com/2073-4409/11/2/269
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