Clinical Benefits Associated With Evinacumab in Pediatric Patients With Homozygous Familial Hypercholesterolemia

Background Homozygous familial hypercholesterolemia (HoFH), characterized by extremely elevated low‐density lipoprotein cholesterol (LDL‐C) due to severely impaired LDL‐C clearance from circulation, remains challenging to treat. Here, we investigated clinical benefits of monoclonal antibody, evinacu...

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Principais autores:	M. D. Reijman, Charlotte Nigmann, D. M. Kusters, R. N. Planken, Christian Loewe, Victor A. Verpalen, G. K. Hovingh, Manuela Neyer, Sophie Draxler‐Dworzak, Katharina Mair, Klaus Arbeiter, Thomas Mueller‐Sacherer, Jaap W. Groothoff, Barbara A. Hutten, Susanne Greber‐Platzer, Albert Wiegman
Formato:	Artigo
Idioma:	Inglês
Publicado:	Wiley 2026-09-01
Series:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Assuntos:	childhood coronary computed tomography angiography evinacumab familial hypercholesterolemia homozygous lipoprotein apheresis
Acceso en liña:	https://www.ahajournals.org/doi/10.1161/JAHA.125.048419
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