Clinical Benefits Associated With Evinacumab in Pediatric Patients With Homozygous Familial Hypercholesterolemia

Background Homozygous familial hypercholesterolemia (HoFH), characterized by extremely elevated low‐density lipoprotein cholesterol (LDL‐C) due to severely impaired LDL‐C clearance from circulation, remains challenging to treat. Here, we investigated clinical benefits of monoclonal antibody, evinacu...

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Bibliografiske detaljer

Principais autores:	M. D. Reijman, Charlotte Nigmann, D. M. Kusters, R. N. Planken, Christian Loewe, Victor A. Verpalen, G. K. Hovingh, Manuela Neyer, Sophie Draxler‐Dworzak, Katharina Mair, Klaus Arbeiter, Thomas Mueller‐Sacherer, Jaap W. Groothoff, Barbara A. Hutten, Susanne Greber‐Platzer, Albert Wiegman
Format:	Artigo
Sprog:	Inglês
Udgivet:	Wiley 2026-09-01
Serier:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Fag:	childhood coronary computed tomography angiography evinacumab familial hypercholesterolemia homozygous lipoprotein apheresis
Online adgang:	https://www.ahajournals.org/doi/10.1161/JAHA.125.048419
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