Multi-Substituted Quinolines as HIV-1 Integrase Allosteric Inhibitors
Allosteric HIV-1 integrase (IN) inhibitors, or ALLINIs, are a new class of antiviral agents that bind at the dimer interface of the IN, away from the enzymatic catalytic site and block viral replication by triggering an aberrant multimerization of the viral enzyme. To further our understanding of th...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI AG
2022-07-01
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| Schriftenreihe: | Viruses |
| Schlagworte: | |
| Online-Zugang: | https://www.mdpi.com/1999-4915/14/7/1466 |
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