The IQGAP1-claudin cell junction axis in cisplatin-induced epithelial damage

Abstract Dysfunction of epithelial cell contacts associates with a myriad of human diseases. Cisplatin is an effective antineoplastic agent where it interferes with DNA replication in proliferating cells, but it causes kidney epithelial damage by unclear mechanism(s). We hypothesized that cisplatin...

詳細記述

書誌詳細

主要な著者:	Yusuf Barudi, Xiuzhen Fan, Kenneth W. Jenkins, Shubhra Kanti Dey, Lance Dworkin, Evgeny Yakirevich, Mahasin A. Osman
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2026-03-01
シリーズ:	Cell Communication and Signaling
主題:	Cell contacts Signaling scaffold Claudin Chronic kidney damage Chemotherapy
オンライン･アクセス:	https://doi.org/10.1186/s12964-026-02797-0
タグ:	タグ追加 タグなし, このレコードへの初めてのタグを付けませんか!