PTEN‐mediated dephosphorylation of 53BP1 confers cellular resistance to DNA damage in cancer cells
Homologous recombination (HR) repair for DNA double‐strand breaks (DSBs) is critical for maintaining genome stability and conferring the resistance of tumor cells to chemotherapy. Nuclear PTEN which contains both phosphatidylinositol 3,4,5‐trisphosphate 3‐phosphatase and protein phosphatase plays a...
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| Автори: | , , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Wiley
2024-03-01
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| Серія: | Molecular Oncology |
| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1002/1878-0261.13563 |
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