The Peritoneal Surface Proteome in a Model of Chronic Peritoneal Dialysis Reveals Mechanisms of Membrane Damage and Preservation

Peritoneal dialysis (PD) fluids are cytotoxic to the peritoneum. Recent studies have shown that alanyl-glutamine (AlaGln) modulates the cellular stress response, improves mesothelial cell survival, reduces submesothelial thickening in experimental models of PD, and in clinical studies improves PD ef...

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Detalhes bibliográficos

Principais autores:	Michael Boehm, Rebecca Herzog, Florian Klinglmüller, Anton M. Lichtenauer, Anja Wagner, Markus Unterwurzacher, Robert H. J. Beelen, Seth L. Alper, Christoph Aufricht, Klaus Kratochwill
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2019-05-01
coleção:	Frontiers in Physiology
Assuntos:	N(2)-alanyl-L-glutamine cytoprotective additive in vivo proteomics mesothelial cells peritoneal immune response PD rat model
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fphys.2019.00472/full
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