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Local Immunometabolic Intervention With Alanyl-Glutamine Resolves Peritoneal Dialysis-Induced Immune Cell Dysfunction

Introduction: Peritoneal dialysis (PD) is the most prevalent home-based dialysis therapy. However, chronic exposure to metabolically imbalanced high-glucose PD fluids is associated with infectious complications and morphological changes that limit PD duration and patient survival. Here, we analyzed...

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I tiakina i:
Ngā kaituhi matua: Rebecca Herzog, Lisa Daniel-Fischer, Fabian Eibensteiner, Isabel J. Sobieszek, Markus Unterwurzacher, Juan Manuel Sacnun, Phoebe K.T. Uhl, Elisabeth Lang, Anja Wagner, Franz König, Seth L. Alper, Luke C. Davies, Christoph Aufricht, Andreas Vychytil, Klaus Kratochwill
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2026-05-01
Rangatū:Kidney International Reports
Ngā marau:
amino acid metabolism
glucose metabolism
glutamine
immune paralysis
peritoneal inflammation
peritonitis
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2468024926025738
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