Local Immunometabolic Intervention With Alanyl-Glutamine Resolves Peritoneal Dialysis-Induced Immune Cell Dysfunction

Introduction: Peritoneal dialysis (PD) is the most prevalent home-based dialysis therapy. However, chronic exposure to metabolically imbalanced high-glucose PD fluids is associated with infectious complications and morphological changes that limit PD duration and patient survival. Here, we analyzed...

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Hlavní autoři:	Rebecca Herzog, Lisa Daniel-Fischer, Fabian Eibensteiner, Isabel J. Sobieszek, Markus Unterwurzacher, Juan Manuel Sacnun, Phoebe K.T. Uhl, Elisabeth Lang, Anja Wagner, Franz König, Seth L. Alper, Luke C. Davies, Christoph Aufricht, Andreas Vychytil, Klaus Kratochwill
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2026-05-01
Edice:	Kidney International Reports
Témata:	amino acid metabolism glucose metabolism glutamine immune paralysis peritoneal inflammation peritonitis
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2468024926025738
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