The EMT activator ZEB1 accelerates endosomal trafficking to establish a polarity axis in lung adenocarcinoma cells

The way in which metastatic tumour cells control endocytic vesicular trafficking networks to establish a front-rear polarity axis that facilitates motility remains unclear. Here, the authors show that the EMT activator ZEB1 influences vesicular trafficking dynamics to execute cell polarity change.

Dettagli Bibliografici

Autori principali:	Priyam Banerjee, Guan-Yu Xiao, Xiaochao Tan, Veronica J. Zheng, Lei Shi, Maria Neus Bota Rabassedas, Hou-fu Guo, Xin Liu, Jiang Yu, Lixia Diao, Jing Wang, William K. Russell, Jason Roszik, Chad J. Creighton, Jonathan M. Kurie
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2021-11-01
Serie:	Nature Communications
Accesso online:	https://doi.org/10.1038/s41467-021-26677-y
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