Mitochondria-targeting ACSL6 variant drives mitochondrial fragmentation potentially through local DHA-CoA production
Abstract Fatty acids are metabolized into fatty acid-coenzyme A (CoA) by the acyl-CoA synthetase (ACS). Acsl6 is an ACS that preferentially uses polyunsaturated fatty acids such as docosahexaenoic acid (DHA) as substrates. Acsl6 is essential for maintaining normal brain function, visual function, an...
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| المؤلفون الرئيسيون: | , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Nature Portfolio
2026-04-01
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| سلاسل: | Scientific Reports |
| الموضوعات: | |
| الوصول للمادة أونلاين: | https://doi.org/10.1038/s41598-026-46977-x |
| الوسوم: |
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