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The evolving landscape of regulatory T cells in leukemia: from mechanisms to advanced immunotherapeutic strategies

The tumor microenvironment (TME) in hematologic malignancies constitutes a dynamic ecosystem supporting leukemogenesis, therapeutic resistance, and immune evasion. Key drivers of this immunosuppressive network are regulatory T cells (Tregs), a CD4+ subset conventionally defined by FoxP3 and CD25 exp...

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Bibliografische gegevens
Hoofdauteurs: Huili Xu, Xiaoli Zhang, Jun Zhang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2026-05-01
Reeks:Frontiers in Immunology
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Online toegang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1822997/full
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