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Advances in strategies to improve the immunotherapeutic efficacy of chimeric antigen receptor-T cell therapy for lymphoma

Chimeric antigen receptor-T (CAR-T) cell therapy is a precise immunotherapy for lymphoma. However, its long-term efficacy faces many challenges related to tumor cell heterogeneity, interference from immunosuppressive microenvironments, CAR-T cell exhaustion, and unmanageable adverse events. Diverse...

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Главные авторы: Tianshu Yu, Xianhuo Wang, Ou Bai, Huilai Zhang, Wenbin Qian
Формат: Artigo
Язык:Inglês
Опубликовано: China Anti-Cancer Association 2025-04-01
Серии:Cancer Biology & Medicine
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Online-ссылка:https://www.cancerbiomed.org/content/22/4/301
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