Impact of single-nucleotide variants and individual characteristics on adverse events of L-asparaginase in children with acute lymphoblastic leukemia

IntroductionL-Asparaginase (L-Asp) is a key drug in the treatment of acute lymphoblastic leukemia (ALL); however, it is commonly associated with the occurrence of adverse events (AE). Risk factors such as age, sex, nutritional status, and some single nucleotide variants (SNVs) in specific genes coul...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Jesús Alonso Gándara-Mireles, Ismael Lares-Asseff, Elio Aarón Reyes Espinoza, Verónica Loera Castañeda, Lourdes Patricia Córdova Hurtado, Flor de María Reyes Gutiérrez, Antonio Sandoval-Cabrera, Ignacio Villanueva Fierro, Julio Cesar Grijalva Ávila, Claudia Castro Arreola, Leslie Patrón-Romero, Horacio Almanza Reyes
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-10-01
Edice:	Frontiers in Pharmacology
Témata:	single-nucleotide variants L-asparaginase adverse events leukemia children
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1423049/full
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!