Metformin relieves bone cancer pain by reducing TGFβRI-TRPV1 signaling in rats

Common cancer complications include bone cancer pain (BCP), which was not sufficiently alleviated by traditional analgesics. More safe and effective therapy was urgent needed. Metformin relieved osteoarthritis pain, but the analgesia of Metformin in BCP was not well studied. The study aimed to explo...

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Principais autores:	Fang Zhou, He-Ya Qian, Ke Wang, Yong-Juan Gu, Pei-Lin Liu, Ling Zhang, Long Chen, Yu Song, Ya-Nan Chen, Hai-Long Zhang
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Elsevier 2024-08-01
סדרה:	Heliyon
נושאים:	Bone cancer pain Metformin TGFβ1 TGFβRI TRPV1
גישה מקוונת:	http://www.sciencedirect.com/science/article/pii/S2405844024110225
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