Allosteric regulation of the 20S proteasome by the Catalytic Core Regulators (CCRs) family

Abstract Controlled degradation of proteins is necessary for ensuring their abundance and sustaining a healthy and accurately functioning proteome. One of the degradation routes involves the uncapped 20S proteasome, which cleaves proteins with a partially unfolded region, including those that are da...

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Autores principales:	Fanindra Kumar Deshmukh, Gili Ben-Nissan, Maya A. Olshina, Maria G. Füzesi-Levi, Caley Polkinghorn, Galina Arkind, Yegor Leushkin, Irit Fainer, Sarel J. Fleishman, Dan Tawfik, Michal Sharon
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2023-05-01
Colección:	Nature Communications
Acceso en línea:	https://doi.org/10.1038/s41467-023-38404-w
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