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The C-Terminus of the PSMA3 Proteasome Subunit Preferentially Traps Intrinsically Disordered Proteins for Degradation

The degradation of intrinsically disordered proteins (IDPs) by a non-26S proteasome process does not require proteasomal targeting by polyubiquitin. However, whether and how IDPs are recognized by the non-26S proteasome, including the 20S complex, remains unknown. Analyses of protein interactome dat...

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Главные авторы: Assaf Biran, Nadav Myers, Shirel Steinberger, Julia Adler, Marianna Riutin, Karin Broennimann, Nina Reuven, Yosef Shaul
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI AG 2022-10-01
Серии:Cells
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Online-ссылка:https://www.mdpi.com/2073-4409/11/20/3231
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