Functional Effects In Silico Prediction for Androgen Receptor Ligand-Binding Domain Novel I836S Mutation

Over 1000 mutations are described in the androgen receptor (AR) gene. Of those, about 600 were found in androgen insensitivity syndrome (AIS) patients, among which 400 mutations affect the ligand-binding domain (LBD) of the AR protein. Recently, we reported a novel missense mutation c.2507T>G I836S...

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Principais autores:	Alexey Rayevsky, Dmytro Sirokha, Dariia Samofalova, Dmytro Lozhko, Olexandra Gorodna, Inga Prokopenko, Liudmyla Livshits
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-07-01
coleção:	Life
Assuntos:	androgen receptor ligand-binding domain mutation molecular modeling molecular dynamics time isolated RMSF
Acesso em linha:	https://www.mdpi.com/2075-1729/11/7/659
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