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Synthesis of Hydantoin Androgen Receptor Antagonists and Study on Their Antagonistic Activity

Hydroxymethylthiohydantoin, hydroxymethylthiohydantoin, and hydantoin, containing a pyridine group, were synthesized to study their androgen receptor antagonistic activities. Among them, compounds <b>6a</b>/<b>6c</b>/<b>7g</b>/<b>19a</b>/<b>19b</b> exhibited excellent androgen receptor antagonistic...

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Autors principals: Longjun Ma, Yan Zhou, Dehua Yang, Ming-Wei Wang, Wei Lu, Jiyu Jin
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2022-09-01
Col·lecció:Molecules
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Accés en línia:https://www.mdpi.com/1420-3049/27/18/5867
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