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Conformational regulation of Escherichia coli DNA polymerase V by RecA and ATP.

Mutagenic translesion DNA polymerase V (UmuD'2C) is induced as part of the DNA damage-induced SOS response in Escherichia coli, and is subjected to multiple levels of regulation. The UmuC subunit is sequestered on the cell membrane (spatial regulation) and enters the cytosol after forming a UmuD'2C...

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Autors principals: Malgorzata M Jaszczur, Dan D Vo, Ramunas Stanciauskas, Jeffrey G Bertram, Adhirath Sikand, Michael M Cox, Roger Woodgate, Chi H Mak, Fabien Pinaud, Myron F Goodman
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2019-02-01
Col·lecció:PLoS Genetics
Accés en línia:https://doi.org/10.1371/journal.pgen.1007956
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