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Targeting of the Fun30 nucleosome remodeller by the Dpb11 scaffold facilitates cell cycle-regulated DNA end resection

DNA double strand breaks (DSBs) can be repaired by either recombination-based or direct ligation-based mechanisms. Pathway choice is made at the level of DNA end resection, a nucleolytic processing step, which primes DSBs for repair by recombination. Resection is thus under cell cycle control, but a...

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Detalhes bibliográficos
Principais autores: Susanne CS Bantele, Pedro Ferreira, Dalia Gritenaite, Dominik Boos, Boris Pfander
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications Ltd 2017-01-01
Colecção:eLife
Assuntos:
Acesso em linha:https://elifesciences.org/articles/21687
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