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Targeting of the Fun30 nucleosome remodeller by the Dpb11 scaffold facilitates cell cycle-regulated DNA end resection

DNA double strand breaks (DSBs) can be repaired by either recombination-based or direct ligation-based mechanisms. Pathway choice is made at the level of DNA end resection, a nucleolytic processing step, which primes DSBs for repair by recombination. Resection is thus under cell cycle control, but a...

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Hlavní autoři: Susanne CS Bantele, Pedro Ferreira, Dalia Gritenaite, Dominik Boos, Boris Pfander
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications Ltd 2017-01-01
Edice:eLife
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On-line přístup:https://elifesciences.org/articles/21687
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