Development and validation of a population pharmacokinetic model for lacosamide in adult patients with epilepsy to inform precision dosing
Abstract Background Lacosamide is a third-generation antiseizure medication that reduces seizures by promoting slow inactivation of voltage-gated sodium channels. There are significant interindividual differences in the pharmacokinetics of this drug. The aim of this study was to explore the pharmaco...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMC
2026-03-01
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| Schriftenreihe: | BMC Pharmacology and Toxicology |
| Schlagworte: | |
| Online-Zugang: | https://doi.org/10.1186/s40360-026-01114-2 |
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