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Development and validation of a population pharmacokinetic model for lacosamide in adult patients with epilepsy to inform precision dosing

Abstract Background Lacosamide is a third-generation antiseizure medication that reduces seizures by promoting slow inactivation of voltage-gated sodium channels. There are significant interindividual differences in the pharmacokinetics of this drug. The aim of this study was to explore the pharmaco...

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Bibliografiske detaljer
Principais autores: Lingyan Yu, Fengqian Mao, Shunan Chen, Kangzhen Yu, Yani Hu, Jie Chen, Wei Hu, Zhenwei Yu, Haibin Dai
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-03-01
Serier:BMC Pharmacology and Toxicology
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Online adgang:https://doi.org/10.1186/s40360-026-01114-2
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