HIV-1 cell-to-cell spread overcomes the virus entry block of non-macrophage-tropic strains in macrophages.

Macrophages (MΦ) are increasingly recognized as HIV-1 target cells involved in the pathogenesis and persistence of infection. Paradoxically, in vitro infection assays suggest that virus isolates are mostly T-cell-tropic and rarely MΦ-tropic. The latter are assumed to emerge under CD4+ T-cell paucity...

Fuld beskrivelse

Bibliografiske detaljer

Principais autores:	Mingyu Han, Vincent Cantaloube-Ferrieu, Maorong Xie, Marie Armani-Tourret, Marie Woottum, Jean-Christophe Pagès, Philippe Colin, Bernard Lagane, Serge Benichou
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science (PLoS) 2022-05-01
Serier:	PLoS Pathogens
Online adgang:	https://doi.org/10.1371/journal.ppat.1010335
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!