Atox1 promotes CRC progression by protecting DNA damage through interacts with a novel copper-binding protein PARP1
Abstract The copper chaperone antioxidant 1 (Atox1) is a key driver in several cancers, with increased expression associated with poor survival. Its role in colorectal cancer (CRC) had been largely unexplored. Based on TCGA data and clinical samples, we found elevated Atox1 expression in CRC. Knockd...
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| Principais autores: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BMC
2026-03-01
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| Serija: | Cell Communication and Signaling |
| Teme: | |
| Online dostop: | https://doi.org/10.1186/s12964-026-02854-8 |
| Oznake: |
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