Evaluation of ATOX1 as a Potential Predictive Biomarker for Tetrathiomolybdate Treatment of Breast Cancer Patients with High Risk of Recurrence

Copper plays a key role in cancer metastasis, which is the most common cause of cancer death. Copper depletion treatment with tetrathiomolybdate (TM) improved disease-free survival in breast cancer patients with high risk of recurrence in a phase II clinical trial. Because the copper metallochaperon...

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Autores principales:	Stéphanie Blockhuys, Camilla Hildesjö, Hans Olsson, Linda Vahdat, Pernilla Wittung-Stafshede
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2021-12-01
Colección:	Biomedicines
Materias:	breast cancer ATOX1 copper depletion tetrathiomolybdate event-free survival biomarker
Acceso en línea:	https://www.mdpi.com/2227-9059/9/12/1887
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