Combinatorial macrophage induced innate immunotherapy against Ewing sarcoma: Turning “Two Keys” simultaneously

Abstract Background Macrophages play important roles in phagocytosing tumor cells. However, tumors escape macrophage phagocytosis in part through the expression of anti-phagocytic signals, most commonly CD47. In Ewing sarcoma (ES), we found that tumor cells utilize dual mechanisms to evade macrophag...

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Bibliografische gegevens

Hoofdauteurs:	Wen Luo, Hai Hoang, Katherine E. Miller, Hongwen Zhu, Serena Xu, Xiaokui Mo, Elizabeth A. R. Garfinkle, Heather Costello, Saranga Wijeratne, Wiebke Chemnitz, Ronan Gandhi, Yanling Liao, Janet Ayello, Aliza Gardenswartz, Jeremy M. Rosenblum, Kevin A. Cassady, Elaine R. Mardis, Dean A. Lee, Timothy P. Cripe, Mitchell S. Cairo
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	BMC 2024-07-01
Reeks:	Journal of Experimental & Clinical Cancer Research
Onderwerpen:	CD47 blockade Chemotherapy Macrophages Ewing sarcoma
Online toegang:	https://doi.org/10.1186/s13046-024-03093-w
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