<it>scribble </it>mutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs
<p>Abstract</p> <p>Background</p> <p>Metastatic neoplasias are characterized by excessive cell proliferation and disruptions to apico-basal cell polarity and tissue architecture. Understanding how alterations in cell polarity can impact upon tumour development is, therefore, a central issue in cance...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMC
2009-09-01
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| Schriftenreihe: | BMC Biology |
| Online-Zugang: | http://www.biomedcentral.com/1741-7007/7/62 |
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