Polarity protein Par6 facilitates the processive phosphorylation of Lgl via a dynamic interaction with aPKC
Abstract Polarity along an apical-basal axis is essential for epithelial cell shape and function. The atypical protein Kinase-C (aPKC) and its regulatory partner Par6 form a complex that is essential for polarization, a primary function of which is to phosphorylate the Lethal giant larvae (Lgl) prot...
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| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
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Nature Portfolio
2025-07-01
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| Sarja: | Communications Biology |
| Linkit: | https://doi.org/10.1038/s42003-025-08401-4 |
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