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Polarity protein Par6 facilitates the processive phosphorylation of Lgl via a dynamic interaction with aPKC

Abstract Polarity along an apical-basal axis is essential for epithelial cell shape and function. The atypical protein Kinase-C (aPKC) and its regulatory partner Par6 form a complex that is essential for polarization, a primary function of which is to phosphorylate the Lethal giant larvae (Lgl) prot...

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Bibliografiset tiedot
Päätekijät: Lior Almagor, William I. Weis
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Portfolio 2025-07-01
Sarja:Communications Biology
Linkit:https://doi.org/10.1038/s42003-025-08401-4
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