Defective Homologous Recombination Repair By Up‐Regulating Lnc‐HZ10/Ahr Loop in Human Trophoblast Cells Induced Miscarriage

Abstract Human trophoblast cells are crucial for healthy pregnancy. However, whether the defective homologous recombination (HR) repair of dsDNA break (DSB) in trophoblast cells may induce miscarriage is completely unknown. Moreover, the abundance of BRCA1 (a crucial protein for HR repair), its recr...

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Detalhes bibliográficos

Principais autores:	Weina Chen, Chenyang Mi, Ying Zhang, Yang Yang, Wenxin Huang, Zhongyan Xu, Jingsong Zhao, Rong Wang, Manli Wang, Shukun Wan, Xiaoqing Wang, Huidong Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2024-04-01
Colecção:	Advanced Science
Assuntos:	environmental BaP or BPDE female trophoblast cells homologous recombination miscarriage non‐coding RNA lnc‐HZ10
Acesso em linha:	https://doi.org/10.1002/advs.202207435
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