Environmental BPDE induced human trophoblast cell apoptosis by up-regulating lnc-HZ01/p53 positive feedback loop

Human trophoblast cell apoptosis may induce miscarriage. Trophoblast cells are sensitive to environmental BaP-7,8-dihydrodiol-9,10-epoxide (BPDE). However, how BPDE induces human trophoblast cell apoptosis is still largely elusive. In this work, we used BPDE-treated human trophoblast cells and villo...

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Autors principals:	Xinying Huang, Chenglong Ma, Wenxin Huang, Mengyuan Dai, Jingjing Yang, Xiaole Xu, Yuanlv Deng, Yang Yang, Huidong Zhang
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2022-06-01
Col·lecció:	Ecotoxicology and Environmental Safety
Matèries:	Environmental BaP or BPDE Non-coding lncRNA-HZ01 Female trophoblast cell apoptosis MDM2/p53/caspase-3 Miscarriage
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S0147651322004043
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