Position Weight Matrix or Acyclic Probabilistic Finite Automaton: Which model to use? A decision rule inferred for the prediction of transcription factor binding sites

Abstract Prediction of transcription factor binding sites (TFBS) is an example of application of Bioinformatics where DNA molecules are represented as sequences of A, C, G and T symbols. The most used model in this problem is Position Weight Matrix (PWM). Notwithstanding the advantage of being simpl...

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Asıl Yazarlar:	Guilherme Miura Lavezzo, Marcelo de Souza Lauretto, Luiz Paulo Moura Andrioli, Ariane Machado-Lima
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Sociedade Brasileira de Genética 2024-01-01
Seri Bilgileri:	Genetics and Molecular Biology
Konular:	Transcription factor binding site position weight matrix ChIP-seq position dependency model comparison
Online Erişim:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572023000700802&tlng=en
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