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Lipase maturation factor 1 is required for endothelial lipase activity[S]

Lipase maturation factor 1 (Lmf1) is an endoplasmic reticulum (ER) membrane protein involved in the posttranslational folding and/or assembly of lipoprotein lipase (LPL) and hepatic lipase (HL) into active enzymes. Mutations in Lmf1 are associated with diminished LPL and HL activities (“combined lip...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Osnat Ben-Zeev, Maryam Hosseini, Ching-Mei Lai, Nicole Ehrhardt, Howard Wong, Angelo B. Cefalù, Davide Noto, Maurizio R. Averna, Mark H. Doolittle, Miklós Péterfy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2011-06-01
Schriftenreihe:Journal of Lipid Research
Schlagworte:
combined lipase deficiency
endoplasmic reticulum
hepatic
metabolism
phospholipases
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S0022227520313341
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