cld and lec23 are disparate mutations that affect maturation of lipoprotein lipase in the endoplasmic reticulum
The mutations cld (combined lipase deficiency) and lec23 disrupt in a similar manner the expression of lipoprotein lipase (LPL). Whereas cld affects an unknown gene, lec23 abolishes the activity of α-glucosidase I, an enzyme essential for proper folding and assembly of nascent glycoproteins. The hyp...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
1999-11-01
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| Colecção: | Journal of Lipid Research |
| Assuntos: | |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S0022227520324287 |
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